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With everything that folks deal with to lose weight naturally, diets that won't work, diet pills that won't do what they are meant to, overpriced home fitness equipment, simply to name a few. It is no wonder that now the latest idea is to combine prescription medications in the hopes that using the combination can have the miraculous results that they can so desperately want and in many cases need. Using two separate drugs to shed weight can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you need to err to the side of caution and allow the FDA do its job and demand some investigation be done so that the public understands the side effects and dangers of the medications before we bring them. Keep in mind that drug companies have been in business to generate money and that they would say everything to keep people on his or her medications. Researchers discovered that participants using this drug to get a year, dropped excess weight within one month and have kept the body weight off through the entire 56 weeks in the study. Contrave is really a combination from the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which can be made up of multiple active ingredient, which can make them more efficient and safer. Combo-pilling may be the newest fad or better yet the newest in the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular may be the fact that by right now there are not any long term prescription slimming capsules that have been authorized by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug may also raise hypertension and heartrate, and shouldn't be used in people who have a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise hypertension and heartrate and must not used in patients with uncontrolled high hypertension, in addition to by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients which has a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients to the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. Most of the combinations which might be used to enhance weight reduction involve an amphetamine and an antidepressant. Phentermine and Prozac can be a popular combination that were around for quite a while, and although it has been around nobody wants to truly combine the two and try to get FDA approval to market it as a weight-loss pill. Right there should raise some red flags if the greedy pharmaceutical companies do not want to be involved in combining medications and selling them something have to be wrong while using combination. In fairness there exists one weight loss combination pill that's in front of the FDA now Contrave?which couples naltrexone, employed to treat alcohol and substance abuse, using the antidepressant bupropion (Wellbutrin, Zyban) it is often given the go ahead to move forward by an FDA advisory committee, but by yet will not be approved. I received the order and it was on time and the pills work great. My wife thanks you, I thank you, the bed thanks you, the room , sheet, etc..... Aaron, Italy But i will say mine were left on the step so maybe they have been delivered ! The products were so cheap compared with my local pharmacy. Landon, France